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In an ideal world, all bioinformatics tools would be made available via the Web as a web service with an API, as well as a standalone package to download for local use. This is rarely the case and sometimes, even where one or the other is available, factors such as ... [Read more...]

Which topics are the most popular at the BioStar bioinformatics Q&A site? One source of data is the tags used for questions. Tags are somewhat arbitrary of course, but fortunately BioStar has quite an active community, so “bad” tags are usually edited to improve them. Hint: if your question ... [Read more...]

See also: Part 1: QTL Analysis and Quantitative Genetics  Part 2: Statistical Methods for QTL Analysis The 'qtl' package in R allows you to implement QTL analysis using the methods I've previously discussed. The code below is adapted from Broman... [Read more...]

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Peter writes: I wonder if part of the drop off is live bloggers moving to platforms like Twitter? I can tell you it seemed like there were almost as many tweets for one SIG (#bosc2011) as for the whole of #ISMB / #ECCB2011, and I personally didn’t post anything to ... [Read more...]

The wordcloud package is word clouds for R with a difference: they look great. Of course, having just analysed online coverage of the ISMB conference, I had to run all 6 906 comments from the 2008-2011 meetings through some code. If you followed along via the Sweave code, I went as far ... [Read more...]

ISMB/ECCB 2011 was held between July 15-19 this year and as in previous years, FriendFeed was used to cover the meeting. Last year, I wrote a post about how to use R to analyse the coverage. I was planning something similar for 2011 when I thought: we have 4 years of ISMB ... [Read more...]

Today a lot of great mails arrived at my inbox. In one of them I was reading I’ve just added your feed to the site. Where did this mail come from? The sender of the email was Tal Galili. He is a researcher in BioStatistics at the Tel Aviv ... [Read more...]

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Complicated calculations usually take a lot of time. So how to know the progress status to estimate how much time the program still needs to finish? [Read more...]

Disease Ontology (DO) provides an open source ontology for the integration of biomedical data that is associated with human disease. DO analysis can lead to interesting discoveries that deserve further clinical investigation. DOSE was designed for semantic similarity measure and enrichment analysis. Read More: 619 Words Totally [Read more...]

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PLINK/SEQ is an open source C/C++ library for analyzing large-scale genome sequencing data. The library can be accessed via the pseq command line tool, or through an R interface. The project is developed independently of PLINK but it's syntax will be f... [Read more...]

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In recently years, high-throughput experimental techniques such as microarray and mass spectrometry can identify many lists of genes and gene products. The most widely used strategy for high-throughput data analysis is to identify different gene clusters based on their expression profiles. Another commonly used approach is to annotate these genes ... [Read more...]

Just found a very nice plugin for using R in Vim. It's unbelievable comfortable! [Read more...]

Just wanted to create an expression, existing of some mathematical annotation and a value of an R object. Wasn't that intuitive! [Read more...]