You may consider R as a big calculator running on different operating systems (Windows, Apple, Unix…). The original interface for R is too simple, so many interfaces are developed for different needs. I will introduce three interfaces of R for people from beginners to professionals.

R commander– Running R like SPSS 

SPSS is probably the most popular point-and-click statistical software.  R commander has similar function like SPSS and is very suitable for SPSS users or R beginners. Some examples could be found in the book, Discovering Statistics Using R.
R commander

RExcel– Running R within Excel

If you still feel uncomfortable about using the unfamiliar interface, why not trying using R within Excel?   RExcel is just the add-in of Excel and you can use R to run more complex models just using Rexcel without seeing R. It also works seamlessly with R commander. Check the book, R through Excel , for more details.

Rstudio– Running R like a pro

Once you are more familiar with R codes, Rstudio is a great interface for debugging and integrating all the materials together.

Tinn-R

Of course, some professionals prefer more functions like using colors to discriminate different codes. Another interesting function of Tinn-R is that it provides the function that let you copy the format of the code (including the color) for MS-Word like the following figure.




You can also try to use Sublime text.